Ulceration of the Cornea

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Ulceration of the Cornea

as a means of determining the classification in most instances, and in doubtful cases the question can almost always be settled by staining and examining a film?a proceeding well within the power of all. Ulcers are divided into (A) Traumatic; (B) Primary and (C) Secondary Corneal infections, and (D) Ulcerations due to tropic disturbances, desiccation or degenerative processes. The primary corne...

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Ulceration of the cornea in rheumatoid arthritis.

Five patients with melting of the cornea in association with rheumatoid arthritis are described. The arthritis was often inactive and without systemic manifestations, in contrast to that seen in association with scleritis. In 3 there was evidence of reduced tear formation, but in none was tear production absent. In 3 patients the lesions healed during treatment with azathioprine or penicillamine.

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Inhibitory effect of a complementary peptide on ulceration in the alkali-injured rabbit cornea.

PURPOSE Two tripeptide chemoattractants, acetyl-proline-glycine-proline (Ac-PGP) and methyl-proline-glycine-proline (Me-PGP), are the primary triggers for early neutrophil invasion into the alkali-injured cornea. In the present study the effectiveness of a complementary peptide designed to inhibit the PGP chemoattractants (arginine-threonine-arginine [RTR] tetrameric peptide) and an apo A-1 mim...

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Epithelial abrasion precipitates stromal ulceration in the vitamin A--deficient rat cornea.

Although the role of vitamin A deficiency in the development of xerophthalmia is well established, there is still some question as to whether the deficiency alone is sufficient cause for the development of keratomalacia. This article describes the clinical, histologic, and microbiologic changes occurring in eyes of vitamin A-deficient rats when keratomalacia-like stromal ulceration is induced b...

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ژورنال

عنوان ژورنال: The Boston Medical and Surgical Journal

سال: 1859

ISSN: 0096-6762,1533-4406

DOI: 10.1056/nejm185904210601202